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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
11.82
Human Site:
T508
Identified Species:
18.57
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
T508
T
P
L
G
E
E
M
T
P
P
P
K
P
P
R
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
T505
T
P
L
G
E
E
M
T
P
P
P
K
P
P
R
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
T621
T
P
L
G
E
E
M
T
P
P
P
K
P
P
R
Dog
Lupus familis
XP_548434
951
104664
R570
S
P
L
G
E
E
M
R
P
P
P
K
P
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
D497
M
K
T
L
S
K
E
D
T
K
P
P
P
K
P
Rat
Rattus norvegicus
O08874
985
112050
E572
T
K
L
D
F
D
L
E
P
E
A
P
P
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
D606
P
L
T
L
E
E
E
D
P
P
P
K
P
P
R
Chicken
Gallus gallus
XP_422357
1013
114806
V644
E
N
G
R
N
S
I
V
P
K
L
Q
P
G
I
Frog
Xenopus laevis
Q7ZX15
486
56292
E176
G
K
V
I
L
V
R
E
K
A
T
G
R
Y
Y
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
T560
N
F
S
E
E
R
P
T
K
P
P
R
L
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
G324
V
M
L
A
E
K
K
G
T
D
E
I
Y
A
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
L384
D
F
T
F
M
K
V
L
G
K
G
S
F
G
K
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
S397
S
Q
E
G
G
A
G
S
P
S
K
D
K
M
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
H627
K
K
I
S
L
Q
T
H
G
R
E
K
L
N
K
Red Bread Mold
Neurospora crassa
P87253
1142
127954
Q754
Q
Q
Q
Q
Q
Q
Q
Q
T
P
Q
Q
V
S
P
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
100
100
86.6
N.A.
13.3
26.6
N.A.
60
13.3
0
26.6
N.A.
13.3
N.A.
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
20
40
N.A.
60
26.6
6.6
33.3
N.A.
20
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
7
0
0
0
7
7
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
0
7
0
14
0
7
0
7
0
0
0
% D
% Glu:
7
0
7
7
47
34
14
14
0
7
14
0
0
0
0
% E
% Phe:
0
14
0
7
7
0
0
0
0
0
0
0
7
0
0
% F
% Gly:
7
0
7
34
7
0
7
7
14
0
7
7
0
14
7
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% H
% Ile:
0
0
7
7
0
0
7
0
0
0
0
7
0
0
14
% I
% Lys:
7
27
0
0
0
20
7
0
14
20
7
40
7
7
14
% K
% Leu:
0
7
40
14
14
0
7
7
0
0
7
0
14
0
7
% L
% Met:
7
7
0
0
7
0
27
0
0
0
0
0
0
7
0
% M
% Asn:
7
7
0
0
7
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
7
27
0
0
0
0
7
0
54
47
47
14
54
34
20
% P
% Gln:
7
14
7
7
7
14
7
7
0
0
7
14
0
0
0
% Q
% Arg:
0
0
0
7
0
7
7
7
0
7
0
7
7
0
34
% R
% Ser:
14
0
7
7
7
7
0
7
0
7
0
7
0
7
0
% S
% Thr:
27
0
20
0
0
0
7
27
20
0
7
0
0
0
0
% T
% Val:
7
0
7
0
0
7
7
7
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
7
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _